Synthetic receptor design
Designing logic-gated receptor systems for T cells that can recognize cancer cells with greater precision and context-awareness.
- T cells
- synthetic receptors
- logic gating
- cancer recognition
projects
Most of these live at the intersection of biology, AI, and the question: what would it take to actually engineer the immune system?
Designing logic-gated receptor systems for T cells that can recognize cancer cells with greater precision and context-awareness.
A tool for designing modular genetic perturbations in T cells — the editing layer of cell engineering.
How T cells recognize cancer — and how sensitivity, specificity, and cell state (including the role of noncoding RNA and lincRNAs) shape whether recognition holds or breaks down.
Research and writing on how memory T cells may shape cancer immunoprevention.
Using computational tools to reason about perturbations, receptor designs, cell states, and experimental design.
Making immunology and cancer biology easier to see, explain, and care about.