about
Cancer immunology, T cells, and editable biology.
I'm Sid. I work across immunology, gene editing, and AI for biology, and I'm most interested in systems that recognize, remember, fail, and repair. This is the longer version.
about
About
I'm Sid. Most of my work circles around cancer immunology, T cells, gene editing, and the problem of making biology more understandable and more editable.
I'm drawn to systems that recognize, remember, fail, repair, and adapt: immune systems, cells, institutions, people, and sometimes software.
- Recognition
- How T cells sense cancer — specificity, sensitivity, context, and state.
- Synthetic receptors
- Logic-gated receptors and circuits that shape what a cell can recognize and when it acts.
- Gene editing
- CRISPR, perturbation design, engineered cells — the editing layer.
- Immunology
- T cells, memory, exhaustion, and cancer immunology.
- AI and tools
- Interfaces that make biology easier to reason through.
- Writing and philosophy
- Uncertainty, selfhood, altruism, medicine, and decision-making.
- Outside the lab
- Biking, cities, food, and long conversations.
history
How the work developed
- 2020–2021First lab
Princess Margaret / UHN — Harding Lab
Cancer biology and DNA damage. Where research stopped being an idea and became something I actually did with my hands.
Princess Margaret / UHN — Harding LabLab bench, microscopy, notebook, or research buildingPrincess Margaret / UHN — Harding Lab - 2022–2023Memory T cells
Salk Institute — Kaech Lab
Memory T cells, immunology, and cancer prevention — work that became a first-author paper in the Journal of Immunology on memory T cells in cancer immunoprevention.
Salk Institute — Kaech LabSalk architecture, lab photo, or T cell sketchSalk Institute — Kaech Lab - 2024–presentEditing & receptor logic
Stanford University / Arc Institute — Roth Lab
CRISPR, T cell engineering, and programmable biology — and the receptor and circuit logic that decides what an engineered cell can sense and do. Still involved.
Stanford University / Arc Institute — Roth LabCRISPR design interface, whiteboard, or wet-lab setupStanford University / Arc Institute — Roth Lab - 2023–presentRecognition & cell state
University of Toronto / Princess Margaret — Brooks Lab
T cell biology and cancer immunology, leaning into immune dysfunction, exhaustion, and cell state (including noncoding RNA / lincRNAs): why cancer recognition holds or breaks down inside tumors.
University of Toronto / Princess Margaret — Brooks LabT cell biology, lincRNA / noncoding RNA notes, or lab notebookUniversity of Toronto / Princess Margaret — Brooks Lab - 2025–presentCurrent direction
Now
Working at the interface of recognition and editing — synthetic receptors, CRISPR, cell state, and AI — to make how T cells recognize cancer more precise, more legible, and more editable.
Current workDesk, notes, code editor, bike, or a T cell recognition sketchNow · building